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Suicide - Medication Side Effects

Updated: Aug 22

Suicide is a tragic event that affects many people and can stem from various factors as listed below. It's important to understand that anyone experiencing suicidal thoughts is not alone and that there are people who care and want to help. Symptoms that someone might be considering suicide include talking about wanting to die, withdrawing from friends and family, and drastic changes in behavior. Recognizing these signs early can be crucial in preventing a tragedy. Here are several factors that can lead to suicide. The suicide rate stands at 14.4 deaths per 100,000 people​ (USAFacts)​.

  1. Mental Health Disorders: Conditions like depression, bipolar disorder, anxiety disorders, and schizophrenia significantly increase the risk of suicide.

  2. Substance Abuse: Abuse of alcohol and drugs can heighten suicidal thoughts and behaviors by impairing judgment and increasing impulsivity.

  3. Chronic Pain or Illness: Living with chronic pain or a debilitating illness can lead to persistent feelings of hopelessness and despair.

  4. Traumatic Experiences: Experiencing trauma, such as physical or sexual abuse, can result in severe emotional distress and suicidal thoughts.

  5. Social Isolation: Loneliness and a lack of social support can contribute to feelings of worthlessness and depression.

  6. Family History: A family history of suicide or mental illness can increase the risk of suicidal behavior.

  7. Financial or Legal Problems: Severe financial stress or legal issues can lead to overwhelming feelings of hopelessness.

  8. Relationship Issues: Problems in relationships, such as divorce, breakups, or the death of a loved one, can trigger suicidal thoughts and behaviors.

  9. Prescription Medication Side Effects: Some medications, particularly certain antidepressants, antipsychotics, and acne medications like isotretinoin (Accutane), can have side effects that include suicidal thoughts.

  10. Previous Suicide Attempts: A history of previous suicide attempts significantly increases the risk of future attempts.

  11. Spiritual Oppression: Feelings of spiritual despair or a sense of spiritual oppression can contribute to suicidal thoughts, particularly in individuals struggling with their faith or experiencing religious conflict. The Bible talks about certain spirits that may affect our well-being.

12. Access to Means: Having access to lethal means, such as firearms or toxic substances, can increase the risk of suicide, especially during a crisis. Here is a list of 30 pharmaceutical medications that have been reported to have suicide as a potential side effect. This is not an exclusive list. Do your research.

  1. Accutane (isotretinoin) - used for severe acne

  2. Prozac (fluoxetine) - an antidepressant (SSRI)

  3. Zoloft (sertraline) - an antidepressant (SSRI)

  4. Paxil (paroxetine) - an antidepressant (SSRI)

  5. Celexa (citalopram) - an antidepressant (SSRI)

  6. Lexapro (escitalopram) - an antidepressant (SSRI)

  7. Effexor (venlafaxine) - an antidepressant (SNRI)

  8. Cymbalta (duloxetine) - an antidepressant (SNRI)

  9. Pristiq (desvenlafaxine) - an antidepressant (SNRI)

  10. Wellbutrin (bupropion) - an antidepressant

  11. Chantix (varenicline) - used for smoking cessation

  12. Xanax (alprazolam) - an anti-anxiety medication

  13. Klonopin (clonazepam) - an anti-anxiety medication

  14. Ambien (zolpidem) - a sleep aid

  15. Lyrica (pregabalin) - used for nerve pain and seizures

  16. Topamax (topiramate) - used for seizures and migraine prevention

  17. Lamictal (lamotrigine) - used for bipolar disorder and seizures

  18. Keppra (levetiracetam) - used for seizures

  19. Seroquel (quetiapine) - an antipsychotic

  20. Abilify (aripiprazole) - an antipsychotic

  21. Risperdal (risperidone) - an antipsychotic

  22. Geodon (ziprasidone) - an antipsychotic

  23. Lithium - used for bipolar disorder

  24. Remeron (mirtazapine) - an antidepressant

  25. Anafranil (clomipramine) - a tricyclic antidepressant

  26. Elavil (amitriptyline) - a tricyclic antidepressant

  27. Norpramin (desipramine) - a tricyclic antidepressant

  28. Tofranil (imipramine) - a tricyclic antidepressant

  29. Zyban (bupropion) - used for smoking cessation

  30. Strattera (atomoxetine) - used for ADHD


These medications can affect individuals differently, and the risk of suicide as a side effect can vary. It is crucial for patients to be closely monitored by healthcare professionals, especially when starting or changing dosages of these medications. Always consult with a healthcare provider regarding potential side effects and risks.

Do not stop taking your medication. Consult with your doctor and make that decision together based on his/her recommendations.


If you or someone you know is struggling with suicidal thoughts, it is vital to seek help immediately. The National Suicide Prevention Lifeline is available 24/7 at 1-800-273-8255. They offer confidential support and connect you with local resources. Additionally, organizations like the Crisis Text Line (text HOME to 741741) and the American Foundation for Suicide Prevention (afsp.org) provide valuable resources and support for those in need. Remember, reaching out for help is a sign of strength, not weakness.

Kim @ Wellness For Life, LLC

Nutritionist/Nutrition Coach

Naturopathic Practitioner

Hormone Specialist

Elite Personal Trainer

Senior Fitness Specialist

Keto Specialist



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